{"product_id":"synthetic-methodologies-biologically-relevant-privileged-scaffold-von-lorenzo-botta","title":"Synthetic Methodologies ~ Biologically Relevant \"Privileged Scaffold\"","description":"\u003cp\u003ePrivileged structures are molecular scaffolds with versatile binding properties, such that a single scaffold is able to provide potent and selective ligands for a range of different biological targets through the simple manipulation of the functional groups. In addition, privileged structures typically exhibit good drug-like properties, which in turn leads to more drug-like compound libraries and leads. In this book the possibility to develop a versatile methodology for the syntheis of biologically relevant privileged scaffolds is deeply explored. The first part of the book is focused on the development of a multicomponent approach for the synthesis of Dihydropirans and Sugars. The second part of the book is focused on the synthesis and the biological evaluation, against HIV virus, of derivatives with a rhodaninc structure. Finally, the third part regards the attemps to synthesize the indenic privileged structure as a strategy to obtain the natural product Cyanosporoside.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659937583\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783659937583","offer_id":39450789937245,"sku":"9783659937583","price":54.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/92e29196-3912-4d3c-a109-30ed5f63b39b.jpg?v=1773122717","url":"https:\/\/shop.autorenwelt.de\/en\/products\/synthetic-methodologies-biologically-relevant-privileged-scaffold-von-lorenzo-botta","provider":"Autorenwelt Shop","version":"1.0","type":"link"}