{"product_id":"proprotein-convertases-von-majambu-mbikay-nabil-g-seidah-hrsg","title":"Proprotein Convertases","description":"\n                                \n                \u003cp\u003e\n                                        Today, activation endoproteolysis of secretory proteins is recognized as a fundamental biological mechanism of spatial and temporal regulation of protein activity as well as of diversification of protein functions.  In \n                    \n                    \u003ci\u003eProprotein Convertases\u003c\/i\u003e\n                                        , experts in the field examine detailed methods involving proprotein convertases, the enzymes mediating this endoproteolysis, which reside within or cycle between the various compartments of the secretory pathway.  Providing a timely assessment of impact of activation\/inactivation endoproteolysis in the secretory pathway, the volume offers a broader perspective on the biochemistry of the PCSKs (proprotein convertases, subtilisin\/kexin-type) by exploring structural and functional analogies with bacterial subtilisin and on the enzymology of endoproteolysis itself by describing the involvement in the process of non-PCSK-type such as cathepsin L.  Written in the highly successful \n                    \n                    \u003ci\u003eMethods in Molecular Biology\u003c\/i\u003e\n                                         series format, chapters include introductions to their specific topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.\n                \n                \u003c\/p\u003e\n                                \n                \u003cp\u003e \u003c\/p\u003e\n                                Meticulous and up-to-date, \n                \n                \u003ci\u003eProprotein Convertases\u003c\/i\u003e\n                                 represents an instructive and useful reference book for all scientists interested in endoproteolytic activation and\/or inactivation of secretory proproteins through limited proteolysis, for experts in the field and newcomers to it as well.\n            \n            \u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9781493961764\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9781617792038\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9781493961764","offer_id":39417256083549,"sku":"9781493961764","price":155.14,"currency_code":"EUR","in_stock":true},{"title":"Hardcover - 9781617792038","offer_id":40570972438621,"sku":"9781617792038","price":106.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/e715725f-2f12-4b5e-9aaa-8421e4ba20a2.jpg?v=1772341922","url":"https:\/\/shop.autorenwelt.de\/en\/products\/proprotein-convertases-von-majambu-mbikay-nabil-g-seidah-hrsg","provider":"Autorenwelt Shop","version":"1.0","type":"link"}