{"product_id":"phospholipid-transfer-protein-and-cholesteryl-ester-transfer-protein-von-riikka-vikstedt","title":"Phospholipid Transfer Protein and Cholesteryl Ester Transfer Protein","description":"\u003cp\u003eCardiovascular diseases are an important cause of  mortality worldwide. They are an entity of diseases  of the heart and vasculature, mainly caused by  atherosclerosis. In atherosclerosis, cholesterol  accumulates in the vessel wall, mainly in the form  of low-density lipoprotein (LDL). High-density  lipoprotein (HDL) protects against atherosclerosis,  as HDL particles accept cellular cholesterol and  transport it to the liver for excretion in a  process called reverse cholesterol transport (RCT).  Phospholipid transfer protein (PLTP) and  cholesteryl ester transfer protein (CETP) are two  key lipid transfer proteins responsible for the  remodeling of HDL particles. The aim of this thesis  was to clarify the role of PLTP and CETP in RCT.  The results indicate that both PLTP and CETP can  remodel HDL as a cholesterol acceptor, which  affects the removal of cholesterol from foam cells.  This thesis is useful to anyone interested in lipid  metabolism. It gives the reader a basic knowledge  about the development of atherosclerosis and  factors affecting that. It is also useful to  professionals giving also a deeper insight to the  world of lipid metabolism.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838318547\"\u003e\u003ch3\u003eThe Role in Reverse Cholesterol Transport\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838318547","offer_id":39497168060509,"sku":"9783838318547","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/7e9d7956-e617-49a9-b471-824ec505aac7.jpg?v=1776145597","url":"https:\/\/shop.autorenwelt.de\/en\/products\/phospholipid-transfer-protein-and-cholesteryl-ester-transfer-protein-von-riikka-vikstedt","provider":"Autorenwelt Shop","version":"1.0","type":"link"}