{"product_id":"optimization-in-drug-discovery-in-vitro-methods-von-gary-w-caldwell-zhengyin-yan-hrsg","title":"Optimization in Drug Discovery","description":"\n                                \n                \u003cp\u003e\n                                        Thoroughly revised and updated, \n                    \n                    \u003ci\u003eOptimization in Drug Discovery: In Vitro Methods, Second Edition\u003c\/i\u003e\n                                         presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity assays. Written for the \n                    \n                    \u003ci\u003eMethods in Pharmacology and Toxicology\u003c\/i\u003e\n                                         series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Expert authors have developed and utilized these in vitro assays to achieve “drug-like” characteristics in addition to efficacy properties and good safety profiles of drug candidates.\n                \n                \u003c\/p\u003e\n                                \n                \u003cp\u003e\n                                        Comprehensive and up-to-date, \n                    \n                    \u003ci\u003eOptimization in Drug Discovery: In Vitro Methods, Second Edition\u003c\/i\u003e\n                                         aims to guide researchers down the difficult path to successful drug discovery and development.\n                \n                \u003c\/p\u003e\n                            \n            \u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9781493960705\"\u003e\u003ch3\u003eIn Vitro Methods\u003c\/h3\u003e\u003c\/div\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9781627037419\"\u003e\u003ch3\u003eIn Vitro Methods\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9781493960705","offer_id":39417230393437,"sku":"9781493960705","price":149.79,"currency_code":"EUR","in_stock":true},{"title":"Hardcover - 9781627037419","offer_id":39467073339485,"sku":"9781627037419","price":213.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/e836613c-70e1-41e7-b262-4e3c90d92ba7.jpg?v=1774588042","url":"https:\/\/shop.autorenwelt.de\/en\/products\/optimization-in-drug-discovery-in-vitro-methods-von-gary-w-caldwell-zhengyin-yan-hrsg","provider":"Autorenwelt Shop","version":"1.0","type":"link"}