{"product_id":"effect-of-super-disintegrants-on-rapid-release-tablets-of-aceclofenac-von-sameer-sajad","title":"EFFECT OF SUPER DISINTEGRANTS ON RAPID RELEASE TABLETS OF ACECLOFENAC","description":"\u003cp\u003eRapid release tablets are preferred by most  physicians because of their ability to attain peak  plasma concentration rapidly, by immediately  disintegrating in gastric fluid.    Pain and inflammation are one of the most common  conditions where rapid action of drug is required.  Aceclofenac is used for various pain and  inflammatory conditions, with fewer side effects  than diclofenac. Aceclofenac is completely absorbed  after oral administration. There are no immediate  release tablets of aceclofenac in market.  In order  to accomplish that task of the formulation of rapid  release tablets and to study the effect of  increasing concentrations of super disintegrant,  different formulations were prepared with different  drug: disintegrants ratio. The various super  disintegrants used were indion- 414 , crospovidone,  crosscarmellose sodium and sodium starch glycolate.  The formulated tablets were evaluated for different  characteristics. The different parameters like  thickness, friability, hardness, weight variation,  drug content were found within limits. Dissolution  profile was studied using USP-2 dissolution  apparatus.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783843350402\"\u003e\u003ch3\u003eRAPID RELEASE TABLETS FORMULATION AND EVALUATION\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783843350402","offer_id":39469985267805,"sku":"9783843350402","price":68.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/0a4a7aed-f7a7-4550-975a-c5dec5befc37.jpg?v=1770701475","url":"https:\/\/shop.autorenwelt.de\/en\/products\/effect-of-super-disintegrants-on-rapid-release-tablets-of-aceclofenac-von-sameer-sajad","provider":"Autorenwelt Shop","version":"1.0","type":"link"}