{"product_id":"dna-hydroxymethylation-in-non-coding-repeat-expansion-disorders-von-rustam-esanov","title":"DNA Hydroxymethylation in Non-coding Repeat Expansion Disorders","description":"\u003cp\u003eMy research is focused on the repeat expansion disorders, a family of disorders that result from the repetitive microsatellite sequence within the gene. In particular, this thesis investigates two non-coding repeat expansion disorders: C9orf72-associated Amyotrophic Lateral Sclerosis (C9-ALS) and the Fragile X Syndrome (FXS). Our group was the first to report the presence of 5-hydroxymethylcytosine, a novel epigenetic mark and active DNA demethylation intermediate, at the expanded loci of patients with C9-ALS and FXS.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783330653122\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783330653122","offer_id":39428799496285,"sku":"9783330653122","price":67.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/74348a23-224a-411d-9040-1f95cd2db680.jpg?v=1774675964","url":"https:\/\/shop.autorenwelt.de\/en\/products\/dna-hydroxymethylation-in-non-coding-repeat-expansion-disorders-von-rustam-esanov","provider":"Autorenwelt Shop","version":"1.0","type":"link"}