{"product_id":"correlation-of-ppar-diabetic-nephropathy-von-hanan-hanna","title":"Correlation of PPAR \u0026 Diabetic Nephropathy","description":"\u003cp\u003eDiabetic nephropathy (DN) is an important and often life-threatening microvascular complication of diabetes mellitus (DM). It is characterized by persistent albuminuria in the range of 30¿299 mg\/24 h (microalbuminuria), it has been shown to be the earliest sign of renal change.Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that play pivotal roles in the regulation of a very large number of biological processes, such as cell proliferation, cell differentiation, cell death, and inflammatory responses. PPARs include three known subtypes PPAR ¿, PPAR ¿, and PPAR¿\/¿. It plays many functional roles in different organs and tissues; adipocyte differentiation, lipid and glucose homeostasis, and insulin sensitivity.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786205514641\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9786205514641","offer_id":40753987059805,"sku":"9786205514641","price":43.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/ac7b7e00-a7be-4712-a9c6-206b4392e7a4.png?v=1759214019","url":"https:\/\/shop.autorenwelt.de\/en\/products\/correlation-of-ppar-diabetic-nephropathy-von-hanan-hanna","provider":"Autorenwelt Shop","version":"1.0","type":"link"}