{"product_id":"cell-signalling-and-molecular-complexes-of-the-trh-receptor-von-zdenka-drastichova","title":"Cell signalling and molecular complexes of the TRH receptor","description":"\u003cp\u003eAll living cells need to perceive different signals from their surroundings. Each cell possesses a complex molecular machinery composed of receptors and other regulatory and accessory proteins that participate in transmission and routing extracellular signals into the cell interior. G-protein-coupled receptors (GPCRs) represent the largest group of membrane-bound receptors, which are extensively studied because of their involvement in the regulation of many cellular functions and processes. The first part of this book provides a comprehensive review of current knowledge regarding GPCRs, G-proteins and their signalling pathways. In the next section, the author describes her own experiments dealing with the thyrotropin-releasing hormone (TRH) receptor. She investigated how sustained stimulation of TRH receptors can affect cellular processes and analysed protein complexes of TRH receptors and their cognate Gq\/11 proteins participating in signal transduction. This book can help students and professionals to get an idea about cellular signalling mediated by the receptors coupled with G-proteins, as well as about some experimental approaches for the exploration of these molecules.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659441998\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783659441998","offer_id":39484148875357,"sku":"9783659441998","price":55.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/a6b28209-997d-4383-b8df-7847a63145c1.jpg?v=1758343667","url":"https:\/\/shop.autorenwelt.de\/en\/products\/cell-signalling-and-molecular-complexes-of-the-trh-receptor-von-zdenka-drastichova","provider":"Autorenwelt Shop","version":"1.0","type":"link"}