{"product_id":"cell-based-therapy-for-chronic-neuropathic-pain-after-cns-injury-von-bryan-hains","title":"Cell-Based Therapy For Chronic Neuropathic Pain After CNS Injury","description":"\u003cp\u003eHemisection spinal cord injury (SCI) in preclinical  models results in pathological and functional  features  that mimic the human condition. Chronic pain  secondary  to neuronal injury is actively and continuously  modulated at multiple locations along the sensory  neuraxis. Here, we describe how pain-processing  neurons  of the spinal cord process and communicate  nociceptive  information in terms of precisely calibrated firing  patterns. We then discuss how several cell types,  with  a focus on 5-HTergic neurons, cause system-wide  interference in nociceptive processing through novel  signaling schema, thus contributing to sensory  network  plasticity and chronic pain.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783844326970\"\u003e\u003ch3\u003eA Neurophysiological Outlook\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783844326970","offer_id":39469961281629,"sku":"9783844326970","price":79.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/06899365-f3fd-4b0c-b997-ec11b346758a.jpg?v=1744102173","url":"https:\/\/shop.autorenwelt.de\/en\/products\/cell-based-therapy-for-chronic-neuropathic-pain-after-cns-injury-von-bryan-hains","provider":"Autorenwelt Shop","version":"1.0","type":"link"}