{"product_id":"c-reactive-protein-crp-and-anti-crp-autoantibodies-in-sle-von-christopher-sjowall","title":"C-reactive protein (CRP) and anti-CRP autoantibodies in SLE","description":"\u003cp\u003eSystemic lupus erythematosus (SLE) is an autoimmune  disease characterized by production of a wide range  of autoantibodies, multiple organ involvement and by  tissue deposition of immune complexes (ICs) in the  inflamed organs. In contrast to most systemic  inflammatory conditions, and despite raised levels  of proinflammatory cytokines, SLE flares are rarely  reflected by elevated C-reactive protein (CRP), an  essential acute-phase reactant in man with homologs  in vertebrates and several invertebrates. As a part  of the innate immune system, CRP binds certain  molecules exposed on the surface of dying  cells\/apoptotic debris. CRP also interacts with IgG- containing ICs, binds Fc receptors and activates the  complement system via C1q. In this book, the  important role of CRP and anti-CRP autoantibodies in  the lupus pathogenesis is highlighted. This book  should be of use for rheumatologists, immunologists,  nephrologists, pathologists and PhD students with an  interest in this particular field of research.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838306407\"\u003e\u003ch3\u003e- a study on the occurrence and clinical  implications of anti-CRP antibodies and CRP-mediated complement activation\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838306407","offer_id":39497092989021,"sku":"9783838306407","price":59.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/b226dcc0-582a-4b36-9937-29dd988f1210.jpg?v=1759295940","url":"https:\/\/shop.autorenwelt.de\/en\/products\/c-reactive-protein-crp-and-anti-crp-autoantibodies-in-sle-von-christopher-sjowall","provider":"Autorenwelt Shop","version":"1.0","type":"link"}