{"product_id":"base-excision-repair-pathway-von-undefined","title":"Base Excision Repair Pathway","description":"\n                                This detailed volume provides a comprehensive set of experimental protocols and useful strategies to examine the repair of damaged bases via the Base Excision Repair (BER) pathway \n                \n                \u003ci\u003ein vitro\u003c\/i\u003e\n                                 and in cells. Beginning with multiple molecular and cellular techniques to examine the excision of damaged bases from double-stranded DNA or DNA wrapped in a nucleosome, the book continues with sections covering procedures to detect and quantify the damaged bases, protein DNA crosslinks, and double-strand breaks, experimental procedures to identify DNA repair protein interactome by conventional tandem affinity purification followed by mass spectroscopy analysis, as well as the analysis of genome-wide binding of DNA repair proteins and copy number variations of the DNA damage response gene in tumors. Written for the highly successful \n                \n                \u003ci\u003eMethods in Molecular Biology\u003c\/i\u003e\n                                 series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. \n                \n                \u003cbr\u003e\n                                Authoritative and practical, \n                \n                \u003ci\u003eBase Excision Repair Pathway: Methods and Protocols\u003c\/i\u003e\n                                 serves as a valuable resource for novices and experts trying to examine the repair of various types of DNA lesions \n                \n                \u003ci\u003ein vitro\u003c\/i\u003e\n                                 and in cell by the distinct set of proteins in the BER pathway.\n            \n            \u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9781071633755\"\u003e\u003ch3\u003eMethods and Protocols\u003c\/h3\u003e\u003c\/div\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9781071633724\"\u003e\u003ch3\u003eMethods and Protocols\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9781071633755","offer_id":49936304472389,"sku":"9781071633755","price":149.79,"currency_code":"EUR","in_stock":true},{"title":"Hardcover - 9781071633724","offer_id":46989390152005,"sku":"9781071633724","price":213.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/e92acf5d-a75f-4321-badd-ea8e6cbd8dfc.jpg?v=1772342961","url":"https:\/\/shop.autorenwelt.de\/en\/products\/base-excision-repair-pathway-von-undefined","provider":"Autorenwelt Shop","version":"1.0","type":"link"}