{"product_id":"asymmetric-aldol-reactions-von-aswini-kumar-giri-und-saumen-hajra","title":"Asymmetric Aldol Reactions","description":"\u003cp\u003eChiral auxiliary based and organocatalyzed aldol reactions have been used for the asymmetric synthesis of various natural products. These reactions steps have been used in synthesizing ¿-butyrolactone containing natural products and their analogs. An asymmetric route for one-pot synthesis of trans- and cis-4,5-disubstituted-¿-butyrolactones via reagent sequence controlled syn- and anti- aldol reactions of N-succinyl-2-oxazolidinone are described. Mechanistic studies are discussed. Using these asymmetric syn- and anti-aldol reactions of chiral N-succinyl-2-oxazolidinones, trans-paraconic acids and cis-paraconic acids are synthesized in both of their enantiomeric forms. Enantioselective one-pot synthesis of ¿-(hydroxyalkyl)-¿-butyrolactones employing cross-aldol reaction catalyzed by an organocatalyst is described. Efficient routes for the asymmetric synthesis of (¿)-enterolactone, natural hydroxyenterolactone and its analog utilizing organocatalytic asymmetric cross-aldol reaction and C-alkylation as the key steps are achieved. Similar routes have provided chiral intermediates, which could be converted to epi-isohydroxymatairesinol and (7¿R)-7¿-hydroxymatairesinol.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783639713312\"\u003e\u003ch3\u003eSynthesis of Paraconic Acids \u0026amp; Lignans\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783639713312","offer_id":39467280564317,"sku":"9783639713312","price":89.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/a9ca3090-0159-4671-ba24-7870627df40d.jpg?v=1775882476","url":"https:\/\/shop.autorenwelt.de\/en\/products\/asymmetric-aldol-reactions-von-aswini-kumar-giri-und-saumen-hajra","provider":"Autorenwelt Shop","version":"1.0","type":"link"}