{"product_id":"antibody-drug-conjugates-von-undefined-1","title":"Antibody Drug Conjugates","description":"\n                                \n                \u003cp\u003eThis volume provides a comprehensive recapitulation of structure-activity relationship (SAR) from a mechanism of action point of view for this unique therapeutic modality, in a largely disease agnostic manner. From a disease biology and pharmacology perspective, the cellular target and drug-conjugate selection, considerations on liker -chemistry and -antibody ratio, and formulation science and technology, to get from bench to bedside (i.e. from a laboratory to the systemic circulation in a patient). The book also provides an understanding around target binding and drug\/\"payload\" release mechanisms. Furthermore, pharmacokinetic and safety pharmacological aspects from a regulatory and clinical perspective are discussed, along with current chemistry, manufacturing, controls guidance and emerging novel delivery devices or technologies.\u003c\/p\u003e\n                                \n                \n                \u003cp\u003e \u003c\/p\u003e\n                                \n                \n                \u003cp\u003e\n                                        The key differentiation in \n                    \n                    \u003cem\u003eAntibody Drug Conjugates\u003c\/em\u003e\n                                         is the clinical and development discussion, that offers pragmatic considerations in medical product development, IP, regulatory considerations, among others. Furthermore, we discuss the topic as a platform, in a disease agnostic manner.\n                \n                \u003c\/p\u003e\n                            \n            \u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783031893186\"\u003e\u003ch3\u003eDesign, Discovery, and Development\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Hardcover - 9783031893186","offer_id":56980718616901,"sku":"9783031893186","price":139.09,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/67538492-8a3f-43d4-a567-f36a6ffb79e8.jpg?v=1774758274","url":"https:\/\/shop.autorenwelt.de\/en\/products\/antibody-drug-conjugates-von-undefined-1","provider":"Autorenwelt Shop","version":"1.0","type":"link"}