{"product_id":"analytical-studies-on-a-standardized-extract-of-withania-somnifera-l-von-hafsa-ahmad-anil-dwivedi-sarvesh-paliwal","title":"Analytical studies on a standardized extract of Withania somnifera L.","description":"\u003cp\u003eWithania somnifera Dunal (Ashwagandha) is an Indian medicinal plant with significant pharmacological properties like adaptogenic, antioxidant, hypoglycemic and anti-stroke effects. Several of its chemotypes includes NMITLI-101, NMITLI-118, NMITLI-128. The present work elaborates phytochemical and analytical studies on NMITLI118RT+ a candidate drug under the CSIR umbrella (derived from a new chemotype of W. somnifera). Here we report the development validation and applications of a simple, rapid and reliable isocratic HPLC method for quantification of Withanolide A in NMITLI118RT+ on a CN column utilizing gliclazide as an internal standard which could detect Withanolide A at about 3.8 min and gliclazide (internal standard) at about 4.8 min with a linearity range of 2-20 µg\/mL. A second method here reports the development and validation of a simple isocratic method for simultaneous estimation of Withanolide A and Withanone (sesquiterpene lactone markers) established on a C-18; 3µ column which could detect Withanolide A and Withanone at retention times of about 20.7 min and 21.6 min respectively in the linearity range of 2-50 µg\/mL for both.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783330343207\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783330343207","offer_id":39422303436893,"sku":"9783330343207","price":35.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/8af53cc2-cfaf-408d-bad6-e69a6286ef17.jpg?v=1770096714","url":"https:\/\/shop.autorenwelt.de\/en\/products\/analytical-studies-on-a-standardized-extract-of-withania-somnifera-l-von-hafsa-ahmad-anil-dwivedi-sarvesh-paliwal","provider":"Autorenwelt Shop","version":"1.0","type":"link"}