{"product_id":"adiponectin-implications-in-health-and-diseases-von-seema-gupta-v-n-satyawali-und-sanjeev-kumar-shukla","title":"Adiponectin : Implications in Health and Diseases","description":"\u003cp\u003eAdiponectin is the name originated from its distinctive molecular characteristics (¿adipö + ¿nectin¿ = ¿adiponectin¿) as it is a product of novel gene apM1 which is specific to adipocytes and uniquely possess a collagen-like domain with a nectin-like adherent property. Adiponectin is the most abundant peptide secreted by adipocytes, whose altered levels play a central role in obesity-related diseases, including insulin resistance\/type 2 diabetes and cardiovascular disease. It is known to exert anti-diabetic and anti-atherosclerotic effects via adiponectin receptors (Adipors); AdipoR1 and AdipoR2. Adiponectin has direct actions in liver, skeletal muscle and the vasculature. Adiponectin administration in humans and rodents has insulin-sensitizing, anti-atherogenic, and anti-in¿ammatory effects and in certain settings, also decreases body weight. Therefore, adiponectin replacement therapy in humans may suggest potential versatile therapeutic targets in the treatment of obesity, insulin resistance\/type 2 diabetes, cardiovascular disease and atherosclerosis.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786138920915\"\u003e\u003ch3\u003eAdiponectin\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9786138920915","offer_id":40149284651101,"sku":"9786138920915","price":45.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/42abfe43-8428-4f54-8555-b9407d64af2f.jpg?v=1775195212","url":"https:\/\/shop.autorenwelt.de\/en\/products\/adiponectin-implications-in-health-and-diseases-von-seema-gupta-v-n-satyawali-und-sanjeev-kumar-shukla","provider":"Autorenwelt Shop","version":"1.0","type":"link"}